People Type: Trainer

Biography The goal of my research is to understand the molecular basis by which animals and their natural microbiota form specific, reproducible interactions. Microbial symbioses are prevalent in animal biology, and often, as in the case of humans, the animal host is born devoid of its natural symbionts and must acquire microbial partners from the …

Biography Viruses The Mehle lab studies the replication machinery of bunyaviruses and influenza virus, so-called “cap snatching” viruses. Using biochemistry, molecular virology and genetics, we tease apart the function of the viral replication complex with an ultimate goal to stop infection by these medically relevant pathogens.

Biography Mohr’s research goal is to improve the health of children impacted by infections in pregnancy. She currently studies congenital Zika virus infection in a translational macaque model. The Mohr Research Group’s objective is to define the infection’s pathogenesis and long–term neurodevelopment to ultimately identify novel therapeutic targets to improve health outcomes.

Biography Fungal Pathogenesis, Immunology Our laboratory focuses on the host response to biofilm infections, with the goal of devising new approaches for the diagnosis and treatment of these common infections. Patients with indwelling medical devices, such as venous catheters, are at risk for invasive disease caused by various fungal and bacterial pathogens. In these patients, …

Biography Globally, there are more than 30 million individuals living with HIV/AIDS, a number that is growing by approximately 3 million each year. The overarching goal of my laboratory is to contribute meaningfully to the global response to HIV. My laboratory studies the interplay of cellular immune responses, viral genetics, and host genomics in HIV …

Biography Immunology, Immunopathology My research lab is interested in understanding the host immune response to HIV and the effect that HIV-infection has on host immunity to other pathogens. HIV+ immunocompromised individuals cannot mount robust immune responses like those who are otherwise healthy. We use nonhuman primates with defined host MHC genetics to understand key factors …

Biography Bacteria, Fungi What forces shape the evolution of human pathogens? In what ways has human evolution been influenced by infectious diseases? How does the environment affect population-level patterns of infectious disease? These are some of the broad questions we tackle by studying genetic and other types of data from humans and human pathogens. We …

Biography My laboratory takes a synthetic biology approach to designing proteins with new functions and engineering microbes for biosynthesis or bioremediation. We are particularly focused on designing proteins that respond to new ligands, with the goal of making novel protein-based small molecule sensors. We use these small-molecule sensors, along with high-throughput genome engineering, to engineer microbes to produce valuable …