TRAINING GRANT
Biography LAB WEBSITE: https://www.vetmed.wisc.edu/people/wsalgado/ FOCUS GROUPS: Cell Adhesion & Cytoskeleton; Molecular & Genome Biology of Microbes RESEARCH DESCRIPTION: The vascular endothelium is recognized as the target of pathological inflammation as well as the cause of vascular pathologies. Infective endocarditis is, by definition, an infection of the heart endothelium. Endothelial cell responses critically contribute to early …
Biography Bacterial Pathogenesis, Immunology Our lab is interested in how intracellular pathogens parasitize host cells and how the host, in turn, recognizes these pathogens and defends against them. We use the bacterium Listeria monocytogenes, a Gram positive foodborne pathogen, as a model organism to address these questions. L. monocytogenes is capable of infecting a wide …
Biography Bacteria, Symbiosis, Host Response Microbial communities associated with herbivores are fundamental to ecosystem functioning in almost all environments on Earth. Specifically, these communities facilitate the conversion of plant biomass into nutrients usable by their host, thereby bridging primary producers and secondary consumers. My research is focused on understanding the evolution and ecology of herbivore-associated …
Biography Host Response CD8 T cells play a critical role in defense against viral, intracellular bacterial, and protozoon infections. We are interested in studying the regulation of CD8 T-cell homeostasis during acute and chronic viral infections using the well-characterized mouse model of lymphocytic choriomeningitis virus (LCMV) infection. In an acute LCMV infection, the principal focus …