Rob Striker, PhD

Position title: Medicine and Medical Microbiology & Immunology

Email: rtstriker@wisc.edu

Viruses, Translational Research

Dr Striker is interested in control of human RNA viruses including Hepatitis C Virus (HCV), Dengue Virus, and Human immunodeficiency virus (HIV). His research team has multiple bench top and clinical research projects going on currently, and the unifying theme of these projects is to more fully capitalize on viral genetics to understand and ultimately eradicate specific viral pathogens. The team analyzes clinical databases, and performs wet lab experiments including mass spectrometry and other functional data with viral genotype. For example, current clinical genotyping methods for HCV convey only a small amount of the useful information that can theoretically be applied to treatment decisions. They recently identified a novel recombinant genotype 2/1 HCV and critical viral polymorphisms associated with response to cyclophilin inhibitors and outcome in liver transplant patients. His mass spectrometry expertise and interest in host cell kinases has led to a multi lab effort to develop kinase inhibitors as antibiotics.